Clomid (Serophene) and Letrozole (Femara) are medications used to induce ovulation and are frequently used for women with ovulatory problems. These tablets are taken orally for five days of the menstrual cycle with the amount of medication being adjusted until there is proof of ovulation. While you are using Clomid or Letrozole, you will need to see your provider for a “Clomid check” or “Letrozole check” at the beginning of each cycle. These visits are scheduled with the onset of your period and involve a pelvic exam to assure that the ovaries are not enlarged. After the examination, you and your provider will discuss the plan for your next cycle. You may be instructed to keep a temperature chart or use ovulation predictor kits (OPKs) to help determine which day you ovulate.